novos_labs
NOVOS Core Clinical
In stock · Sold by Athletonic
About this product
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First-Of-Its-Kind Clinically Studied Longevity Solution
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•
NOVOS Core Clinical demonstrated statistically significant support for biological systems predictive of lifespan and healthspan* -
•
Developed with scientists & MDs from Harvard Medical School & MIT -
•
Now available at the Mayo Clinic Store & recommended by 1,500+ MDs and clinicians -
•
Backed by 7+ years of R&D
3000+ REVIEWS
Over 10 million doses served
Member of:
Available at:
Mayo Clinic, Mayo Clinic Store, Erewhon, Equinox, The Four Seasons, and Sunlife Organics are trademarks of their respective owners.
*Claims are based on randomized, placebo-controlled human clinical research on the finished NOVOS Core Clinical formulation, along with mechanistic and preclinical studies. In vitro and animal studies are not indicative of impact on humans.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Mayo Clinic, Mayo Clinic Store, Erewhon, Equinox, The Four Seasons, and Sunlife Organics are trademarks of their respective owners.
*Claims are based on randomized, placebo-controlled human clinical research on the finished NOVOS Core Clinical formulation, along with mechanistic and preclinical studies. In vitro and animal studies are not indicative of impact on humans.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Chris, Founder of NOVOS, explains the effect sizes and significance of the NOVOS Core Clinical placebo-controlled clinical study.
NOVOS Core Clinical
Read the Science
Chris, Founder of NOVOS, explains the effect sizes and significance of the NOVOS Core Clinical placebo-controlled clinical study.
NOVOS Core Clinical
See the Science
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“In a sea of generic supplement suppliers with just a packaging and marketing department,
NOVOS’ commitment to research is a clear outlier.”
– Forbes
NOVOS Core Clinical
The first formulation designed to address all 12 biological Hallmarks of Aging — now supported by randomized, placebo-controlled human clinical research showing statistically significant results over placebo across validated functional markers of vascular aging and overall aging, alongside years of mechanistic and preclinical lifespan research.
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Available at:
Member of:
Disclaimer: Mayo Clinic and Mayo Clinic Store are trademarks of their respective owners. No endorsement implied.
“It has been a pleasure to watch NOVOS take a disciplined, biology-first approach in a space that too often prioritizes hype over evidence. What stood out to us was the seriousness of the scientific framework—mechanistic grounding, preclinical data, and an emerging human evidence base—combined with a willingness to engage in rigorous evaluation rather than shortcuts.”
– Dr. Doina Kulick, Lead Physician, Longevity Medicine Program at Mayo Clinic Arizona
NOVOS Core Clinical
The first formulation designed to address all 12 biological Hallmarks of Aging— now supported by randomized, placebo-controlled human clinical research showing statistically significant results over placebo across validated functional markers of vascular aging and overall aging, alongside years of mechanistic and preclinical lifespan research.
NOVOS Core Clinical is the first formulation designed around all 12 biological Hallmarks of Aging, developed with leading longevity scientists and physicians specializing in aging biology.
Backed by more than seven years of R&D, it has been evaluated in randomized, double-blind, placebo-controlled human clinical research demonstrating statistically significant effects across validated measures of endothelial function, arterial flexibility, and systolic blood pressure in the normal range, with effect sizes among the largest reported in published human research for a supplement, nutritional, or lifestyle intervention.
Built as a coordinated, multi-pathway system rather than a single-ingredient solution, NOVOS Core Clinical is designed to support multiple aging-related systems at once. In addition to vascular outcomes, research has observed favorable shifts in biological age markers measured epigenetically and improvements in skin firmness in preliminary human studies, alongside customer-reported benefits such as steadier energy, mental clarity, mood balance, and sleep consistency†. The formulation is further supported by mechanistic studies and preclinical lifespan research, providing multi-level scientific evidence that NOVOS Core Clinical supports foundational aspects of healthy aging biology.*
†Customer-reported outcomes and small scale studies. Individual results will vary.
A system designed to support the biology of aging itself
Aging doesn’t happen in one place. It emerges from interconnected biological processes that influence vascular function, cellular energy production, tissue renewal, and resilience across the body.
NOVOS Core Clinical was intentionally designed around the biology of aging itself — not individual symptoms — by supporting all 12 biological Hallmarks of Aging simultaneously. Developed with scientists and physicians affiliated with institutions including Harvard Medical School, MIT, and the Salk Institute, the formulation is built as a coordinated system designed for ingredient synergy rather than a collection of isolated or trendy ingredients.
Because these foundational systems shape how the body functions day to day, supporting them can influence performance, resilience, and overall well-being long before later-life outcomes become relevant.
Built on evidence, not theory
NOVOS Core Clinical is supported by multiple layers of research:
- Mechanistic studies to understand how it influences aging-related biological pathways
- Preclinical lifespan studies in mice, where animals receiving NOVOS Core Clinical Clinical lived over 18% longer on average (animal models do not predict human outcomes and are not indicative of impact on humans)
- Randomized, placebo-controlled human clinical research using validated functional biomarkers commonly applied in cardiovascular and aging science
This multi-level approach reflects an uncommon standard of scientific validation for a nutritional formulation — testing the complete system rather than relying on individual ingredient claims.
What the formulation is designed to support
Cellular energy & metabolic efficiency
Supports mitochondrial and metabolic pathways involved in cellular energy production to help maintain stamina, clarity, and daily recovery.
Healthy cellular renewal
Supports the body’s natural renewal and turnover processes that help maintain tissue function over time.
Cellular resilience & stability
Supports DNA stability, cellular stress-response pathways, and healthy inflammatory balance to promote long-term cellular function.
Protein quality & cellular communication
Supports proteostasis, extracellular matrix structure, and intercellular signaling — helping tissues remain coordinated and responsive with age.
Why this approach is different
Most supplements focus on isolated ingredients or single outcomes, while few are rigorously evaluated as complete formulations in randomized, placebo-controlled human clinical trials using validated functional biomarkers.
NOVOS Core Clinical was designed to support the biology of aging as a connected system and evaluated as a complete formulation through mechanistic research, preclinical lifespan studies, and human clinical trials — not trends, theories, or ingredient-by-ingredient claims.*
Few dietary supplements are evaluated this way, testing the complete finished formula in humans rather than relying on ingredient-level assumptions.
*These statements have not been evaluated by the Food and Drug Administration. This product/information is not intended to diagnose, treat, cure, or prevent any disease.
Each ingredient in NOVOS Core Clinical was selected based on scientific evidence and is either naturally present in human biology or derived from compounds found in nature. Together, they were chosen for their roles in aging-related biological pathways and for their established safety profiles in human research.
1. Calcium Alpha-Ketoglutarate (Ca-AKG) - A compound naturally present in human metabolism that supports mitochondrial energy production and cellular resilience.
2. Fisetin - A polyphenol found in strawberries and other fruits that supports cellular renewal and healthy inflammatory balance.
3. Pterostilbene - An antioxidant compound found in blueberries that supports vascular and metabolic health.
4. Glucosamine Sulfate – Naturally occurring in connective tissues, supports joint and extracellular matrix integrity.
5. Glycine – An amino acid abundant in collagen that supports recovery, detoxification, and restorative sleep.
6. Magnesium Malate – A form of magnesium involved in ATP production that supports energy metabolism and muscle function.
7. L-Theanine – An amino acid found in green tea that supports calm focus and stress resilience.
8. Rhodiola Rosea – An adaptogenic root traditionally used to support stamina, mental performance, and stress response.
9. Gingerols & Shogaols – Bioactive compounds from ginger that support healthy inflammatory signaling and digestive comfort.
10. Hyaluronic Acid – A molecule naturally present in skin and joints that supports hydration, elasticity, and tissue resilience.
11. Vitamin C – An essential nutrient found in fruits and vegetables that supports collagen production, antioxidant protection, and synergizes with CaAKG.
12. Micro-dosed Lithium – A trace mineral found naturally in water and foods that supports neuronal signaling and mood balance.
These statements have not been evaluated by the Food and Drug Administration. This product/information is not intended to diagnose, treat, cure, or prevent any disease.
Placebo-Controlled Human Clinical Trial Cardiovascular function was selected as the first human system to measure because vascular biology changes early with age and reflects whole-body resilience.
NOVOS Core Clinical was evaluated in a randomized, double-blind, placebo-controlled human clinical trial conducted by university researchers in adults aged 40+. The study assessed validated functional biomarkers commonly used in cardiovascular and aging research.
Compared with placebo, NOVOS Core Clinical demonstrated statistically significant differences across multiple measures of vascular function:
- +3.4% improvement in endothelial function (Flow-Mediated Dilation, FMD) observed shortly after the first dose and sustained over six months
- −1.18 m/s difference in arterial stiffness (Pulse Wave Velocity) at six months
- −8.5 mmHg difference in systolic blood pressure, supporting healthy levels already within the normal range
Effect sizes across these independent vascular biomarkers are among the largest reported in published human research for a nutritional intervention, supplement, or lifestyle modification, including aerobic exercise, providing rare human evidence that a multi-pathway formulation can measurably influence aging-related physiology.*
👉 Read the clinical trial summary
Individual responses vary. Not every person will experience the same magnitude of change.
Preclinical Lifespan Study (Animal Model)
In a controlled mouse lifespan study, animals receiving NOVOS Core Clinical lived over 18% longer on average than controls.
While animal studies do not predict human outcomes, lifespan models are a foundational step in aging research for evaluating long-term, system-level biological effects before human trials.
👉 View the lifespan study
Mechanistic Research (Formulation Design)
NOVOS Core Clinical was developed through mechanistic research examining how ingredient combinations interact with aging-related biological pathways, including DNA protection, cellular senescence, cellular inflammation protection.
This work confirmed formulation design, dosing, and ingredient synergy, ensuring the product was built as an integrated system rather than a collection of isolated compounds.
👉 Explore the mechanistic studies
Epigenetic Aging Analysis
NOVOS has supported independent DNA methylation–based epigenetic age testing, which measures patterns in your DNA that scientists use to estimate biological age over time.
In an exploratory analysis of first-time NOVOS Core Clinical users tested before and after six months of use, follow-up results showed favorable directional shifts in these validated epigenetic biomarkers, consistent with a slower pace of age-related biological change. These tests are research tools used to study aging biology and do not diagnose disease or predict lifespan.*
This was an observational, real-world evaluation rather than a controlled clinical trial.
👉 Learn about our epigenetic research
Skin Elasticity Study (Instrument-Measured)
In a preliminary human study using an indentometer — a scientific device that objectively measures skin firmness — participants showed an average 22% increase in skin elasticity after six months, with some reporting visible improvements within weeks.
These findings suggest that supporting foundational biological pathways may also help maintain skin firmness, structure, and resilience over time.*
This was a small pilot evaluation intended to generate preliminary signals.
👉 View the skin study details
Why This Approach Is Different
Most supplements rely on ingredient-level claims. NOVOS Core Clinical has been rigorously evaluated as a complete formulation across mechanistic research, preclinical lifespan studies, and randomized, placebo-controlled human clinical research, reflecting how aging actually works: as an interconnected biological system rather than isolated symptoms.
*These statements have not been evaluated by the Food and Drug Administration. This product/information is not intended to diagnose, treat, cure, or prevent any disease.
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.truemed-instructions{ border-top: 2px solid #8E8A84; border-bottom: 2px solid #8E8A84; padding-bottom: 15px; }
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- 🫀 Vascular Aging Support (Clinically Studied)
- 🧬 12 Hallmarks of Aging Addressed
- ⚡ Cellular Energy & Recovery
- 🧠 Brain Function & Emotional Balance
- ✨ Skin Structure & Renewal
- 🛡️ Whole-Body Longevity Resilience
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jQuery(document).ready(function ($) { (function() { const $group = $('.product-selector-1'); const $wrapper = $group.find('.product-option-wrap:has(> .separator)');
if (!$group.length || $wrapper.length label.multiple-subscription-option)'); if ($activeOption.length) { const $radio = $activeOption.find('.plan-radio'); if ($radio.length) { return $radio.attr('data-billing-period') || null; } } return null; }
function getDefaultSubtitle(period) { if (!period) { return 'Auto ships every 12 months'; }
const periodLower = period.toLowerCase();
if (periodLower.includes('year') || periodLower.includes('annual') || periodLower.includes('12')) { return 'Auto ships every 12 months'; }
if (periodLower.includes('6')) { return 'Auto ships every 6 months'; }
if (periodLower.includes('month') && (periodLower.includes('1') || !periodLower.match(/\d/))) { return 'Auto ships every month'; }
return 'Auto ships every 12 months'; }
function normalizePeriodKey(period) { if (!period) return null; const periodLower = period.toLowerCase(); if (periodLower.includes('year') || periodLower.includes('annual') || periodLower.includes('12')) { return 12; } if (periodLower.includes('6')) { return 6; } if (periodLower.includes('month') && (periodLower.includes('1') || !periodLower.match(/\d/))) { return 1; } return null; }
function applyContent() { const period = getSelectedPeriod(); const periodKey = normalizePeriodKey(period); let subtitle = staticSubtitle || getDefaultSubtitle(period); let benefits = staticBenefits;
if (dynamicConfig && periodKey && dynamicConfig[periodKey]) { if (dynamicConfig[periodKey].subtitle) { subtitle = dynamicConfig[periodKey].subtitle; } if (dynamicConfig[periodKey].benefits) { benefits = Array.isArray(dynamicConfig[periodKey].benefits) ? dynamicConfig[periodKey].benefits.join('\\A') : dynamicConfig[periodKey].benefits.replace(/\n/g, '\\A'); } }
updateContent(subtitle, benefits); }
function find12MonthOption($scope) { const $searchRoot = $scope && $scope.length ? $scope : $group; let $found = null; $searchRoot.find('.single-purchase-option:has(> label.multiple-subscription-option)').each(function() { const $option = $(this); if ($option.css('display') === 'none' || $option.is(':hidden')) { return true; // continue. } const $radio = $option.find('.plan-radio'); if ($radio.length) { const period = $radio.attr('data-billing-period') || ''; const periodLower = period.toLowerCase(); if (periodLower.includes('year') || periodLower.includes('annual') || periodLower.includes('12')) { $found = $option; return false; // break. } } }); return $found; }
function getPrimaryRadio($option) { const $checkedRadio = $option.find('.plan-radio:checked'); if ($checkedRadio.length) { return $checkedRadio.first(); } const $billingRadio = $option.find('.plan-radio[data-billing-period]:enabled'); if ($billingRadio.length) { return $billingRadio.first(); } const $enabledRadio = $option.find('.plan-radio:enabled'); if ($enabledRadio.length) { return $enabledRadio.first(); } return $option.find('.plan-radio').first(); }
function markUserPlanInteraction() { userHasSelectedPlan = true; }
function findFirstVisibleSubscriptionOption($scope) { const $searchRoot = $scope && $scope.length ? $scope : $group; let $found = null;
$searchRoot.find('> .single-purchase-option:has(> label.multiple-subscription-option)').each(function() { const $option = $(this); if ($option.css('display') === 'none' || $option.is(':hidden')) { return true; // continue. } $found = $option; return false; // break. });
return $found; }
function enforceAnnualDefaultSelection($scope, forceSelection) { const $wrappers = $scope && $scope.length ? $scope : $group.find('.product-option-wrap:has(> .separator)');
$wrappers.each(function() { const $currentWrapper = $(this); const $individualOption = $currentWrapper.find('> .separator ~ .single-purchase-option:has(> label.individual-purchase)'); const $subscriptionOptions = $currentWrapper.find('> .single-purchase-option:has(> label.multiple-subscription-option)');
const $annualOption = find12MonthOption($currentWrapper); const $targetOption = ($annualOption && $annualOption.length) ? $annualOption : findFirstVisibleSubscriptionOption($currentWrapper);
if (!$targetOption || !$targetOption.length) { return; }
const hasIndividualChecked = $individualOption.find('.plan-radio:checked').length > 0; const targetChecked = $targetOption.find('.plan-radio:checked').length > 0; const targetActive = $targetOption.hasClass('active');
if (!forceSelection) { if (userHasSelectedPlan || hasIndividualChecked || (targetChecked && targetActive)) { return; } }
$individualOption.find('.plan-radio').prop('checked', false); $subscriptionOptions.find('.plan-radio').prop('checked', false); $individualOption.removeClass('active'); $subscriptionOptions.removeClass('active');
const $targetRadio = getPrimaryRadio($targetOption); if ($targetRadio.length) { $targetRadio.prop('checked', true).trigger('change'); } $targetOption.addClass('active');
syncActiveClasses($currentWrapper); applyContent(); handleIndividualPricing($currentWrapper); }); }
function ensureSubscriptionRadioFallback($scope) { const $wrappers = $scope && $scope.length ? $scope : $group.find('.product-option-wrap:has(> .separator)');
$wrappers.each(function() { const $currentWrapper = $(this); $currentWrapper.addClass('novos-has-radio-fallback');
if (!$currentWrapper.children('.novos-subscription-radio-fallback').length) { $currentWrapper.append(''); } }); }
function syncWrapperSelectionClasses($scope) { const $wrappers = $scope && $scope.length ? $scope : $group.find('.product-option-wrap:has(> .separator)'); ensureSubscriptionRadioFallback($wrappers);
$wrappers.each(function() { const $currentWrapper = $(this); const $individualOption = $currentWrapper.find('> .separator ~ .single-purchase-option:has(> label.individual-purchase)'); const $subscriptionOptions = $currentWrapper.find('> .single-purchase-option:has(> label.multiple-subscription-option)');
const hasIndividualChecked = $individualOption.find('.plan-radio:checked').length > 0; const hasSubscriptionChecked = $subscriptionOptions.find('.plan-radio:checked').length > 0; const hasIndividualActive = $individualOption.hasClass('active'); const hasSubscriptionActive = $subscriptionOptions.filter('.active').length > 0;
let selectedType = null; if (hasIndividualChecked || (!hasSubscriptionChecked && hasIndividualActive)) { selectedType = 'individual'; } else if (hasSubscriptionChecked || hasSubscriptionActive) { selectedType = 'subscription'; }
$currentWrapper.toggleClass('novos-individual-selected', selectedType === 'individual'); $currentWrapper.toggleClass('novos-subscription-selected', selectedType === 'subscription'); }); }
function handleIndividualPricing($scope) { const $wrappers = $scope && $scope.length ? $scope : $group.find('.product-option-wrap:has(> .separator)');
$wrappers.each(function() { const $currentWrapper = $(this); const $subscriptionOptions = $currentWrapper.find('> .single-purchase-option:has(> label.multiple-subscription-option)'); const $individualOption = $currentWrapper.find('> .separator ~ .single-purchase-option:has(> label.individual-purchase)');
const isIndividualActive = $individualOption.hasClass('active') || $individualOption.find('.plan-radio:checked').length > 0;
$subscriptionOptions.removeClass('show-fallback-pricing');
if (isIndividualActive) { const $twelveMonth = find12MonthOption($currentWrapper); if ($twelveMonth && $twelveMonth.length) { $twelveMonth.addClass('show-fallback-pricing'); } } }); }
function syncActiveClasses($scope) { const $wrappers = $scope && $scope.length ? $scope : $group.find('.product-option-wrap:has(> .separator)');
$wrappers.each(function() { const $currentWrapper = $(this);
// Find which radio button is actually checked in this wrapper only const $individualOption = $currentWrapper.find('> .separator ~ .single-purchase-option:has(> label.individual-purchase)'); const $subscriptionOptions = $currentWrapper.find('> .single-purchase-option:has(> label.multiple-subscription-option)');
const hadIndividualActive = $individualOption.hasClass('active'); const $hadActiveSubscription = $subscriptionOptions.filter('.active').first();
const $checkedIndividual = $individualOption.find('.plan-radio:checked'); const $checkedSubscription = $subscriptionOptions.find('.plan-radio:checked');
// Remove all active classes first $individualOption.removeClass('active'); $subscriptionOptions.removeClass('active');
// Add active class to the option with checked radio if ($checkedIndividual.length > 0) { $individualOption.addClass('active'); return; }
if ($checkedSubscription.length > 0) { $checkedSubscription.closest('.single-purchase-option').addClass('active'); return; }
// Fallback when markup updates delayed checked state but active state was already set. if (hadIndividualActive) { const $fallbackIndividualRadio = getPrimaryRadio($individualOption); if ($fallbackIndividualRadio.length) { $fallbackIndividualRadio.prop('checked', true); } $individualOption.addClass('active'); return; }
if ($hadActiveSubscription.length) { const $fallbackSubscriptionRadio = getPrimaryRadio($hadActiveSubscription); if ($fallbackSubscriptionRadio.length) { $fallbackSubscriptionRadio.prop('checked', true); } $hadActiveSubscription.addClass('active'); } });
syncWrapperSelectionClasses($wrappers); }
$group.on('click', '.single-purchase-option:has(> label.multiple-subscription-option)', function() { markUserPlanInteraction();
const $clicked = $(this); const $currentWrapper = $clicked.closest('.product-option-wrap:has(> .separator)'); const $individualOption = $currentWrapper.find('> .separator ~ .single-purchase-option:has(> label.individual-purchase)'); const $subscriptionOptions = $currentWrapper.find('> .single-purchase-option:has(> label.multiple-subscription-option)');
// Uncheck individual radio button const $individualRadio = $individualOption.find('.plan-radio'); if ($individualRadio.length) { $individualRadio.prop('checked', false); }
// Remove active class from individual option when subscription is clicked $individualOption.removeClass('active');
// Remove active class from all subscription options $subscriptionOptions.removeClass('active');
// Add active class to clicked subscription option $clicked.addClass('active');
// Ensure the radio button in the clicked option is checked const $clickedRadio = getPrimaryRadio($clicked); if ($clickedRadio.length) { $clickedRadio.prop('checked', true).trigger('change'); }
setTimeout(applyContent, 10); setTimeout(function() { syncActiveClasses($currentWrapper); handleIndividualPricing($currentWrapper); }, 10); });
$group.on('change', '.plan-radio', function() { const $currentWrapper = $(this).closest('.product-option-wrap:has(> .separator)'); setTimeout(function() { syncActiveClasses($currentWrapper); applyContent(); handleIndividualPricing($currentWrapper); }, 10); });
$group.on('click', '.variation-dropdown-option', function() { const $currentWrapper = $(this).closest('.product-option-wrap:has(> .separator)'); setTimeout(function() { syncActiveClasses($currentWrapper); applyContent(); handleIndividualPricing($currentWrapper); }, 10); });
$group.on('click', '.single-purchase-option:has(> label.individual-purchase)', function() { markUserPlanInteraction();
const $individualOption = $(this).closest('.product-option-wrap:has(> .separator)') .find('> .separator ~ .single-purchase-option:has(> label.individual-purchase)'); const $currentWrapper = $individualOption.closest('.product-option-wrap:has(> .separator)'); const $subscriptionOptions = $currentWrapper.find('> .single-purchase-option:has(> label.multiple-subscription-option)');
// Uncheck all subscription radio buttons $subscriptionOptions.find('.plan-radio').prop('checked', false);
// Remove active class from subscription options when individual is clicked $subscriptionOptions.removeClass('active');
// Ensure the individual option gets the active class $individualOption.addClass('active');
// Ensure the individual radio is checked const $individualRadio = getPrimaryRadio($individualOption); if ($individualRadio.length) { $individualRadio.prop('checked', true).trigger('change'); }
setTimeout(function() { syncActiveClasses($currentWrapper); handleIndividualPricing($currentWrapper); }, 10); });
$group.on('click', 'ul.flavor-dropdown li', function() { const $currentWrapper = $(this).closest('.product-option-wrap:has(> .separator)'); setTimeout(function() { syncActiveClasses($currentWrapper); applyContent(); handleIndividualPricing($currentWrapper); enforceAnnualDefaultSelection($currentWrapper, false); }, 50); });
$group.on('click', '.flavor-option', function() { const $currentWrapper = $(this).closest('.product-option-wrap:has(> .separator)'); setTimeout(function() { syncActiveClasses($currentWrapper); applyContent(); handleIndividualPricing($currentWrapper); enforceAnnualDefaultSelection($currentWrapper, false); }, 50); });
$group.on('change', 'select[name="attribute_flavor"]', function() { const $currentWrapper = $(this).closest('.product-option-wrap:has(> .separator)'); setTimeout(function() { syncActiveClasses($currentWrapper); applyContent(); handleIndividualPricing($currentWrapper); enforceAnnualDefaultSelection($currentWrapper, false); }, 50); });
// Make the entire subscription wrapper card clickable $group.on('click', '.product-option-wrap:has(> .separator)', function(e) { markUserPlanInteraction();
const $currentWrapper = $(this);
// Don't trigger if clicking on a specific subscription option or individual purchase if ($(e.target).closest('.single-purchase-option:has(> label.multiple-subscription-option)').length || $(e.target).closest('.single-purchase-option:has(> label.individual-purchase)').length) { return; }
// Find the 12-month option and select it const $twelveMonth = find12MonthOption($currentWrapper); if ($twelveMonth && $twelveMonth.length) { const $radio = getPrimaryRadio($twelveMonth); if ($radio.length) { // Uncheck individual radio $currentWrapper.find('> .separator ~ .single-purchase-option:has(> label.individual-purchase) .plan-radio').prop('checked', false);
$radio.prop('checked', true).trigger('change'); $currentWrapper.find('> .single-purchase-option:has(> label.multiple-subscription-option)').removeClass('active'); $currentWrapper.find('> .separator ~ .single-purchase-option:has(> label.individual-purchase)').removeClass('active'); $twelveMonth.addClass('active'); setTimeout(applyContent, 10); setTimeout(function() { syncActiveClasses($currentWrapper); handleIndividualPricing($currentWrapper); }, 10); } } });
window.NovosSubscriptionCustomizer = { setSubtitle: function(subtitle) { staticSubtitle = subtitle; applyContent(); },
setBenefits: function(benefits) { staticBenefits = Array.isArray(benefits) ? benefits.join('\\A') : benefits.replace(/\n/g, '\\A'); applyContent(); },
setDynamicContent: function(config) { dynamicConfig = config; applyContent(); },
reset: function() { staticSubtitle = null; staticBenefits = null; dynamicConfig = null; applyContent(); },
getConfig: function() { return { staticSubtitle: staticSubtitle, staticBenefits: staticBenefits, dynamicConfig: dynamicConfig, currentPeriod: getSelectedPeriod() }; } };
ensureSubscriptionRadioFallback($wrapper); applyContent(); syncActiveClasses($wrapper); handleIndividualPricing();
// Add security text below add-to-cart button if not already present const $addToCart = $group.find('.add-to-cart'); if ($addToCart.length && !$addToCart.find('.novos-security-text').length) { $addToCart.append('
'); }
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Member of:
Available at:
Real People. Real Routines. Aging, Done Differently.
Biotechnology rigor. 7+ years of R&D. A higher standard for longevity.
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FAQ
NOVOS Core Clinical is a dietary supplement, not a medication. If you take prescription medications or manage a medical condition, consult your healthcare professional before use, especially if you are pregnant or nursing, managing blood pressure, bleeding or clotting, or any chronic condition.
NOVOS Core Clinical is the daily foundation. It’s a comprehensive longevity formulation designed to support multiple aging-related biological pathways as a complete system.
Other NOVOS products are designed as targeted add-ons — for example, additional NAD+ or mitochondrial support — and can be layered on top of NOVOS Core Clinical depending on your goals.
Timelines vary by individual.
Some people report noticing day-to-day changes first, such as steadier energy or improved sleep consistency, within the first few weeks. Broader, longer-horizon changes associated with healthy aging biology typically build gradually over weeks to months and depend on baseline health and consistent use.
NOVOS Core Clinical is intended for adults. If you’re under 18, pregnant, or breastfeeding, consult a healthcare professional before use.
NOVOS Core Clinical is designed for one sachet daily. Some individuals choose to take up to two sachets per day. If increasing your intake, consider starting with one sachet for at least a week and consult your healthcare professional if you are sensitive to supplements.
There are two practical ways many people evaluate progress:
How you feel
Some people notice day-to-day changes such as steadier energy, sleep consistency, mood improvements, or overall resilience over time.
What you can measure
NOVOS Core Clinical is designed to support underlying biological systems associated with healthy aging, effects that may not always be immediately perceptible but can be observed through objective measures. In human clinical research, NOVOS Core Clinical demonstrated statistically significant benefits across validated functional biomarkers of cardiovascular function, including endothelial responsiveness, arterial flexibility, and support for healthy blood pressure already within the normal range.*
If you already track general wellness metrics, you may choose to monitor markers such as resting heart rate, sleep patterns, blood pressure, or routine labs with your clinician.
Because these changes reflect foundational physiology, benefits are often gradual and cumulative rather than instant.
NOVOS Core Clinical replaces the need to source and dose multiple individual supplements. Instead of assembling a complex stack, you get a single, research-driven formulation developed and evaluated as a complete system. You’re investing in clinical research, quality controls, and formulation design — often at a comparable or lower total cost than buying similar ingredients separately.
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The Science That Puts
Core Clinical in a Class of Its Own
Supported by over 7 years of research, 400+ ingredient studies, and a rapidly expanding body of clinical and preclinical evidence.
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Placebo-Controlled Human Clinical Trial
CLINICALLY OBSERVED SHIFTS IN VASCULAR AGING MARKERS
- What they did: Independent university investigators conducted a randomized, double-blind, placebo-controlled human clinical trial in adults 40+, evaluating NOVOS Core Clinical as a complete formulation over six months using validated vascular biomarkers.
- What they found: Compared with placebo, NOVOS Core Clinical showed statistically significant improvements in:
• endothelial function (+3.4% FMD)
• arterial flexibility (-1.18 m/s PWV)
• systolic blood pressure (-8.5 mmHg)
Effect sizes were larger than those typically reported for commonly studied supplements and lifestyle approaches, including beetroot/nitrates, cocoa flavanols, omega-3s, DASH-style diets, and aerobic or HIIT exercise. - Why that matters: Randomized human trials demonstrating measurable changes across multiple aging-related systems are exceptionally rare in the supplement category, providing first-of-its-kind human evidence of simultaneous, positive effects on endothelial function, arterial flexibility, and healthy blood pressure already within the normal range from a single, multi-component nutritional intervention.*
Read full clinical summary here
Preclinical Lifespan Study
MOUSE LIFESPAN STUDY
- What they did: Researchers evaluated NOVOS Core Clinical in a controlled preclinical mouse model across the full adult lifespan.
- What they found: Mice receiving NOVOS Core Clinical lived over 18% longer on average than controls — a magnitude of effect uncommon for multi-ingredient formulations and more typically associated with interventions studied in aging biology research.
- Why that matters: Lifespan studies in animals are a foundational step in aging science for assessing whole-body biological effects. While results in animal models do not necessarily predict human outcomes, these findings, alongside mechanistic and human clinical research, provide additional evidence of system-level biological activity in vivo.*
Read full study details here
Epigenetic Aging Analysis
EPIGENETIC AGING ASSESSMENT
- What was done: A group of first-time NOVOS Core Clinical customers completed DNA methylation–based epigenetic age testing through an independent third-party laboratory before and after six months of use, while maintaining their usual diet and lifestyle.
- What was observed: Follow-up testing showed favorable directional shifts in validated epigenetic aging biomarkers, including DunedinPACE, corresponding on average to approximately one month per year in a slower pace of biological aging across the group.
- Why that matters: Epigenetic clocks are widely used research tools that estimate biological aging by analyzing DNA methylation patterns. While these observational results are exploratory and not diagnostic or predictive of individual outcomes, they provide additional real-world data on how NOVOS Core Clinical may support aging-related biology over time.*
Learn more about epigenetic analysis and biological age measurement here
Skin Elasticity Assessment
SKIN HEALTH & FIRMNESS
EVALUATION
- What they did: In a small preliminary pilot evaluation, individuals took NOVOS Core Clinical daily for six months. Skin firmness and elasticity were measured using an indentometer, an objective device commonly used to assess skin mechanical properties.
- What they found: Indentometer measurements showed increases in skin firmness ranging from 12% to 40%, with an average improvement of 22% across the group.
- Why that matters: Indentometer testing provides quantifiable insight into structural skin properties over time. While preliminary, these results suggest that supporting foundational biological pathways may also help maintain skin firmness and resilience.*
Learn more about the skin health assessment here
In Vitro Study
REDUCTION IN DNA STRAND
BREAKS FROM CHEMICAL STRESSORS*
- What they did: University of Bologna researchers evaluated NOVOS Core Clinical in a controlled 3D human skin-cell model exposed to chemical stress, measuring laboratory markers associated with DNA damage and oxidative stress.
- What they found: Cells pre-treated with NOVOS showed lower laboratory signals associated with DNA strand breaks and oxidative stress compared with untreated stressed cells.
- Why that matters: DNA integrity and oxidative stress response are fundamental processes studied in aging biology. These laboratory findings provide mechanistic evidence of cellular resilience, but do not represent effects in humans.*
Read full study here
*Laboratory research only. These findings are from in vitro (cell-based) studies and do not demonstrate effects in humans. Results from laboratory models may not reflect how the product performs in the human body. This product is not intended to diagnose, treat, cure, or prevent any disease.
In Vitro Study
INFLAMMATION SIGNAL MODULATION*
- What they did: Researchers at the Salk Institute for Biological Studies evaluated NOVOS Core Clinical ingredient combinations in controlled neuronal and microglial cell models, measuring laboratory markers associated with cellular stress and inflammatory signaling.
- What they found: The combined formulation demonstrated stronger activity than individual ingredients and favorably reduced nitric oxide output in activated microglial cells — a common laboratory readout used to assess inflammatory signaling in vitro.
- Why that matters: Cellular stress and inflammatory signaling pathways are widely studied in aging biology. These laboratory findings provide mechanistic support for how coordinated ingredient combinations may influence cellular resilience, but do not represent human outcomes.*
Read full study here
*Laboratory research only. These findings are from in vitro (cell-based) studies and do not demonstrate effects in humans. Results from laboratory models may not reflect how the product performs in the human body. This product is not intended to diagnose, treat, cure, or prevent any disease.
In Vitro Study
SENESCENT
CELL SUPPORT*
- What they did: Researchers at Newcastle University tested NOVOS Core Clinical ingredient combinations in human cells grown in the lab that displayed characteristics of cellular senescence — a state where older, stressed cells stop functioning optimally and cause inflammation.
- What they found: The combined formulation showed positive effects on senescent cells, reducing their size by approximately 50%, while healthy, non-senescent cells were not measurably affected.
- Why that matters: Cellular senescence is one of the recognized hallmarks of aging. These laboratory findings help explain how coordinated ingredients may support cellular resilience, but they do not represent effects in humans.*
Read full study here
*Laboratory research only. These findings are from in vitro (cell-based) studies and do not demonstrate effects in humans. Results from laboratory models may not reflect how the product performs in the human body. This product is not intended to diagnose, treat, cure, or prevent any disease.
In Vitro Study
REDUCTION IN
DNA OXIDATIVE DAMAGE*
- What they did: An independent laboratory evaluated NOVOS Core Clinical ingredient combinations in human endothelial cells exposed to irradiation, measuring 8-OHdG — a widely used laboratory marker measuring oxidative DNA damage.
- What they found: Cells pre-treated with the NOVOS Core Clinical formulation showed substantially lower 8-OHdG levels across multiple doses, with laboratory markers up to 77% lower (68% lower on average) compared with untreated stressed cells.
- Why that matters: DNA integrity and oxidative stress responses are fundamental processes studied in aging biology. These laboratory findings provide mechanistic insight into cellular resilience under stress, but do not represent effects in humans.*
Read full study here
*Laboratory research only. These findings are from in vitro (cell-based) studies and do not demonstrate effects in humans. Results from laboratory models may not reflect how the product performs in the human body. This product is not intended to diagnose, treat, cure, or prevent any disease.
Placebo-Controlled Human Clinical Trial
CLINICALLY OBSERVED SHIFTS IN VASCULAR AGING MARKERS
- What they did: Independent university investigators conducted a randomized, double-blind, placebo-controlled human clinical trial in adults 40+, evaluating NOVOS Core Clinical as a complete formulation over six months using validated vascular biomarkers.
- What they found: Compared with placebo, NOVOS Core Clinical showed statistically significant improvements in:
• endothelial function (+3.4% FMD)
• arterial flexibility (-1.18 m/s PWV)
• systolic blood pressure (-8.5 mmHg)
Effect sizes were larger than those typically reported for commonly studied supplements and lifestyle approaches, including beetroot/nitrates, cocoa flavanols, omega-3s, DASH-style diets, and aerobic or HIIT exercise. - Why that matters: Randomized human trials demonstrating measurable changes across multiple aging-related systems are exceptionally rare in the supplement category, providing first-of-its-kind human evidence of simultaneous, positive effects on endothelial function, arterial flexibility, and healthy blood pressure already within the normal range from a single, multi-component nutritional intervention.*
Read full clinical summary here
Preclinical Lifespan Study
MOUSE LIFESPAN STUDY
- What they did: Researchers evaluated NOVOS Core Clinical in a controlled preclinical mouse model across the full adult lifespan.
- What they found: Mice receiving NOVOS Core Clinical lived over 18% longer on average than controls — a magnitude of effect uncommon for multi-ingredient formulations and more typically associated with interventions studied in aging biology research.
- Why that matters: Lifespan studies in animals are a foundational step in aging science for assessing whole-body biological effects. While results in animal models do not necessarily predict human outcomes, these findings, alongside mechanistic and human clinical research, provide additional evidence of system-level biological activity in vivo.*
Read full study details here
Epigenetic Aging Analysis
EPIGENETIC AGING ASSESSMENT
- What was done: A group of first-time NOVOS Core Clinical customers completed DNA methylation–based epigenetic age testing through an independent third-party laboratory before and after six months of use, while maintaining their usual diet and lifestyle.
- What was observed: Follow-up testing showed favorable directional shifts in validated epigenetic aging biomarkers, including DunedinPACE, corresponding on average to approximately one month per year in a slower pace of biological aging across the group.
- Why that matters: Epigenetic clocks are widely used research tools that estimate biological aging by analyzing DNA methylation patterns. While these observational results are exploratory and not diagnostic or predictive of individual outcomes, they provide additional real-world data on how NOVOS Core Clinical may support aging-related biology over time.*
Learn more about epigenetic analysis and biological age measurement here
Skin Elasticity Assessment
SKIN HEALTH & FIRMNESS
EVALUATION
- What they did: In a small preliminary pilot evaluation, individuals took NOVOS Core Clinical daily for six months. Skin firmness and elasticity were measured using an indentometer, an objective device commonly used to assess skin mechanical properties.
- What they found: Indentometer measurements showed increases in skin firmness ranging from 12% to 40%, with an average improvement of 22% across the group.
- Why that matters: Indentometer testing provides quantifiable insight into structural skin properties over time. While preliminary, these results suggest that supporting foundational biological pathways may also help maintain skin firmness and resilience.*
Learn more about the skin health assessment here
In Vitro Study
REDUCTION IN DNA STRAND
BREAKS FROM CHEMICAL STRESSORS*
- What they did: University of Bologna researchers evaluated NOVOS Core Clinical in a controlled 3D human skin-cell model exposed to chemical stress, measuring laboratory markers associated with DNA damage and oxidative stress.
- What they found: Cells pre-treated with NOVOS showed lower laboratory signals associated with DNA strand breaks and oxidative stress compared with untreated stressed cells.
- Why that matters: DNA integrity and oxidative stress response are fundamental processes studied in aging biology. These laboratory findings provide mechanistic evidence of cellular resilience, but do not represent effects in humans.*
Read full study here
*Laboratory research only. These findings are from in vitro (cell-based) studies and do not demonstrate effects in humans. Results from laboratory models may not reflect how the product performs in the human body. This product is not intended to diagnose, treat, cure, or prevent any disease.
In Vitro Study
INFLAMMATION SIGNAL MODULATION*
- What they did: Researchers at the Salk Institute for Biological Studies evaluated NOVOS Core Clinical ingredient combinations in controlled neuronal and microglial cell models, measuring laboratory markers associated with cellular stress and inflammatory signaling.
- What they found: The combined formulation demonstrated stronger activity than individual ingredients and favorably reduced nitric oxide output in activated microglial cells — a common laboratory readout used to assess inflammatory signaling in vitro.
- Why that matters: Cellular stress and inflammatory signaling pathways are widely studied in aging biology. These laboratory findings provide mechanistic support for how coordinated ingredient combinations may influence cellular resilience, but do not represent human outcomes.*
Read full study here
*Laboratory research only. These findings are from in vitro (cell-based) studies and do not demonstrate effects in humans. Results from laboratory models may not reflect how the product performs in the human body. This product is not intended to diagnose, treat, cure, or prevent any disease.
In Vitro Study
SENESCENT
CELL SUPPORT*
- What they did: Researchers at Newcastle University tested NOVOS Core Clinical ingredient combinations in human cells grown in the lab that displayed characteristics of cellular senescence — a state where older, stressed cells stop functioning optimally and cause inflammation.
- What they found: The combined formulation showed positive effects on senescent cells, reducing their size by approximately 50%, while healthy, non-senescent cells were not measurably affected.
- Why that matters: Cellular senescence is one of the recognized hallmarks of aging. These laboratory findings help explain how coordinated ingredients may support cellular resilience, but they do not represent effects in humans.*
Read full study here
*Laboratory research only. These findings are from in vitro (cell-based) studies and do not demonstrate effects in humans. Results from laboratory models may not reflect how the product performs in the human body. This product is not intended to diagnose, treat, cure, or prevent any disease.
In Vitro Study
REDUCTION IN
DNA OXIDATIVE DAMAGE*
- What they did: An independent laboratory evaluated NOVOS Core Clinical ingredient combinations in human endothelial cells exposed to irradiation, measuring 8-OHdG — a widely used laboratory marker measuring oxidative DNA damage.
- What they found: Cells pre-treated with the NOVOS Core Clinical formulation showed substantially lower 8-OHdG levels across multiple doses, with laboratory markers up to 77% lower (68% lower on average) compared with untreated stressed cells.
- Why that matters: DNA integrity and oxidative stress responses are fundamental processes studied in aging biology. These laboratory findings provide mechanistic insight into cellular resilience under stress, but do not represent effects in humans.*
Read full study here
*Laboratory research only. These findings are from in vitro (cell-based) studies and do not demonstrate effects in humans. Results from laboratory models may not reflect how the product performs in the human body. This product is not intended to diagnose, treat, cure, or prevent any disease.
Start now
Human Clinical Trial Results
In a randomized, double-blind, placebo-controlled human clinical trial, NOVOS Core Clinical demonstrated statistically significant improvements versus placebo across validated cardiovascular biomarkers used in aging research.*
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Endothelial Function (Circulation)
NOVOS Core Clinical supported healthy endothelial responsiveness with sustained effects measuring approximately 1.26x to 4.65x of leading studied supplements, outperforming tea polyphenols, cocoa flavanols, beetroot nitrates, and demonstrating effects comparable to those reported for weight loss, aerobic exercise, and resistance training.* Learn more.
Arterial Flexibility (Blood Vessels)
NOVOS Core Clinical helped support healthy arterial flexibility with effect sizes exceeding those reported for magnesium and omega-3s, and comparable to published results for weight loss, DASH heart health diets, and structured exercise — an effect rarely observed with dietary supplements.* Learn more.
Systolic Blood Pressure Support
Supported ~8.5–8.7 mmHg differences in systolic blood pressure vs. placebo in adults already in the normal range, exceeding effect sizes reported for common supplements including beetroot/nitrate and potassium, and demonstrating magnitudes of support comparable to those observed for Mediterranean and DASH-style diets and High Intensity Interval Training (HIIT).* Learn more.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
The first to design a formulation addressing
all 12 biological hallmarks of aging,
years ahead of the field.
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Cellular Cleanup & Quality Control
1. Cellular senescence balance
2. Protein quality control (proteostasis)
3. Autophagy & cellular recycling
Energy & Metabolic Function
4. Mitochondrial energy production
5. Nutrient sensing pathways
6. Gut microbiome balance
Genomic & Epigenetic Stability
7. DNA integrity & maintenance
8. Epigenetic regulation
9. Stem cell health & renewal potential
Inflammation & Tissue Communication
10. Healthy inflammatory balance
11. Intercellular communication
12. Extracellular matrix & tissue structure
Cellular Cleanup & Quality Control
1. Cellular senescence balance
2. Protein quality control (proteostasis)
3. Autophagy & cellular recycling
Energy & Metabolic Function
4. Mitochondrial energy production
5. Nutrient sensing pathways
6. Gut microbiome balance
Genomic & Epigenetic Stability
7. DNA integrity & maintenance
8. Epigenetic regulation
9. Stem cell health & renewal potential
Inflammation & Tissue Communication
10. Healthy inflammatory balance
11. Intercellular communication
12. Extracellular matrix & tissue structure
Start now
What You’ll Actually Feel
& What’s Happening
When you support the fundamental drivers of aging, you optimize how your cells function — and how you look and feel today and for years to come.
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Heart Health
Clinically Studied in a Placebo-Controlled Human Trial
Benefits†
- Support vascular resilience and flexibility
- Help maintain healthy blood flow and blood pressure already within the normal range
- Clinically demonstrated support for key markers of vascular aging
Aging Pathways Supported
- Endothelial function
- Arterial elasticity
- Healthy blood pressure balance
- Cellular resilience & metabolic signaling
†Based on a randomized double-blind placebo controlled human clinical study that measured statistically significant improvements vs. placebo for functional markers of blood flow (FMD), blood vessel elasticity (PWV), and maintenance of blood pressure already in the normal range. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Energy & Stamina
Benefits†
- More consistent, steady energy throughout the day
- Supports stamina and physical capacity
- Many people notice changes within the first few weeks, with continued benefits over time†
Aging Pathways Supported
- Mitochondrial energy production
- Nutrient sensing & metabolic efficiency
- Cellular repair and stress response
†Based on customer-reported outcomes and human clinical research of individual component ingredients of the formulation. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brain & Mood
Benefits†
- Supports focus and clear thinking
- Helps maintain memory and cognitive function
- Supports balanced mood and emotional well-being
Aging Pathways Supported
- Healthy inflammatory balance
- Cellular communication & synaptic function
- Cellular resilience & stress response
†Based on customer-reported outcomes and human clinical research of individual component ingredients of the formulation. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Skin Health
Benefits†
- Supports skin firmness, elasticity, and resilience
- Helps improve the look and feel of skin over time
- Many people notice visible changes within weeks, with continued improvements over months†
Aging Pathways Supported
- Collagen structure & extracellular matrix integrity
- Skin barrier function & hydration balance
- Cellular energy & metabolic processes
†Based on customer-reported outcomes and human clinical research of individual component ingredients of the formulation. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Healthy Aging & Longevity
Benefits†
- Supports long-term vitality and performance as you age
- Coordinated support across multiple biological systems
- One complete daily formula instead of complex supplement stacks
Aging Pathways Supported
- Designed around all 12 biological hallmarks of aging
- Cellular maintenance & resilience
- System-wide metabolic & signaling balance
†Based on a placebo controlled human clinical study that observed statistically significant nutritional support vs. placebo for biological systems predictive of lifespan and healthspan. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Heart Health
Clinically Studied in a Placebo-Controlled Human Trial
Benefits†
- Support vascular resilience and flexibility
- Help maintain healthy blood flow and blood pressure already within the normal range
- Clinically demonstrated support for key markers of vascular aging
Aging Pathways Supported
- Endothelial function
- Arterial elasticity
- Healthy blood pressure balance
- Cellular resilience & metabolic signaling
†Based on a randomized double-blind placebo controlled human clinical study that measured statistically significant improvements vs. placebo for functional markers of blood flow (FMD), blood vessel elasticity (PWV), and maintenance of blood pressure already in the normal range. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Energy & Stamina
Benefits†
- More consistent, steady energy throughout the day
- Supports stamina and physical capacity
- Many people notice changes within the first few weeks, with continued benefits over time†
Aging Pathways Supported
- Mitochondrial energy production
- Nutrient sensing & metabolic efficiency
- Cellular repair and stress response
†Based on customer-reported outcomes and human clinical research of individual component ingredients of the formulation. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brain & Mood
Benefits†
- Supports focus and clear thinking
- Helps maintain memory and cognitive function
- Supports balanced mood and emotional well-being
Aging Pathways Supported
- Healthy inflammatory balance
- Cellular communication & synaptic function
- Cellular resilience & stress response
†Based on customer-reported outcomes and human clinical research of individual component ingredients of the formulation. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Skin Health
Benefits†
- Supports skin firmness, elasticity, and resilience
- Helps improve the look and feel of skin over time
- Many people notice visible changes within weeks, with continued improvements over months†
Aging Pathways Supported
- Collagen structure & extracellular matrix integrity
- Skin barrier function & hydration balance
- Cellular energy & metabolic processes
†Based on customer-reported outcomes and human clinical research of individual component ingredients of the formulation. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Healthy Aging & Longevity
Benefits†
- Supports long-term vitality and performance as you age
- Coordinated support across multiple biological systems
- One complete daily formula instead of complex supplement stacks
Aging Pathways Supported
- Designed around all 12 biological hallmarks of aging
- Cellular maintenance & resilience
- System-wide metabolic & signaling balance
†Based on a placebo controlled human clinical study that observed statistically significant nutritional support vs. placebo for biological systems predictive of lifespan and healthspan. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Timeline
of Change
Clinically observed biological shifts begin early
and build with consistent daily use.
Grounded in human clinical research and supported by mechanistic,
preclinical lifespan, and epigenetic studies.
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Within 2 hours: Clinical research observed early changes in vascular function biomarkers, including endothelial responsiveness and systolic blood pressure signaling.
Feel: Some users report subtle increases in mental clarity and drive after initial use.
Cellular support: Ingredients begin engaging antioxidant and cellular stress-response pathways that support system-level resilience.
Daily energy: More consistent energy as cellular energy pathways adapt to regular use.
Recovery & comfort: Users often report improved day-to-day physical comfort and easier recovery from activity.
Inflammatory balance: Supports healthy inflammatory signaling tied to resilience and repair.
Heart & vessels: Randomized, placebo-controlled human research demonstrated statistically significant differences in vascular aging biomarkers, including arterial flexibility (PWV) and support for healthy blood pressure already within the normal range.
Skin appearance: In a pilot human assessment using objective instrument measurements, participants showed measurable improvements in skin firmness and elasticity over six months, consistent with healthier-looking, more resilient skin.
System-wide longevity support: Ongoing use supports multiple core biological pathways associated with healthy aging through a coordinated, multi-system approach.
Pace of aging*: In epigenetic research testing, participants showed directional changes consistent with a slower pace of biological aging over time.
*Epigenetic analyses are research tools and do not diagnose disease or predict lifespan.
Within 2 hours: Clinical research observed early changes in vascular function biomarkers, including endothelial responsiveness and systolic blood pressure signaling.
Feel: Some users report subtle increases in mental clarity and drive after initial use.
Cellular support: Ingredients begin engaging antioxidant and cellular stress-response pathways that support system-level resilience.
Daily energy: More consistent energy as cellular energy pathways adapt to regular use.
Recovery & comfort: Users often report improved day-to-day physical comfort and easier recovery from activity.
Inflammatory balance: Supports healthy inflammatory signaling tied to resilience and repair.
Heart & vessels: Randomized, placebo-controlled human research demonstrated statistically significant differences in vascular aging biomarkers, including arterial flexibility (PWV) and support for healthy blood pressure already within the normal range.
Skin appearance: In a pilot human assessment using objective instrument measurements, participants showed measurable improvements in skin firmness and elasticity over six months, consistent with healthier-looking, more resilient skin.
System-wide longevity support: Ongoing use supports multiple core biological pathways associated with healthy aging through a coordinated, multi-system approach.
Pace of aging*: In epigenetic research testing, participants showed directional changes consistent with a slower pace of biological aging over time.
*Epigenetic analyses are research tools and do not diagnose disease or predict lifespan.
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Compounding Longevity Benefits
Designed for once-a-day simplicity
Gentle on the stomach, easy to remember
Dissolves easily. No pills. No stacking.
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Why No Other Longevity Product Comes Close
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/* Responsive Design */
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.novos-core-comparision .column.first { flex: 0 0 20% !important; max-width: 20% !important; min-width: 20% !important; }
.novos-core-comparision .heading-wrapper { padding: 18px 24px !important; min-height: 72px !important; }
.novos-core-comparision .column.first .heading-wrapper { padding: 18px 14px !important; }
.novos-core-comparision .heading-wrapper .heading, .novos-core-comparision .heading-wrapper h3, .novos-core-comparision .heading-wrapper .text { font-size: 16px !important; }
.novos-core-comparision .row { padding: 18px 24px !important; font-size: 15px !important; min-height: 72px !important; }
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.novos-core-comparision .wp-block-buttons { padding: 18px 24px !important; min-height: 72px !important; } }
/* Tablets (991px and below) */ @media (max-width: 991px) { .novos-core-comparision { padding: 0 16px !important; }
.novos-core-comparision .novos-comparison-table { border-radius: 20px !important; }
.novos-core-comparision h2, .novos-core-comparision .comparison-title { font-size: 30px !important; margin-bottom: 24px !important; text-align: center !important; }
.novos-core-comparision .column.first { flex: 0 0 22% !important; max-width: 22% !important; min-width: 22% !important; }
.novos-core-comparision .heading-wrapper { padding: 16px 20px !important; min-height: 65px !important; }
.novos-core-comparision .column.first .heading-wrapper { padding: 16px 12px !important; }
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.novos-core-comparision .row { padding: 16px 20px !important; font-size: 14px !important; min-height: 65px !important; }
.novos-core-comparision .column.first .row { padding: 16px 12px !important; font-size: 12px !important; }
.novos-core-comparision .wp-block-buttons { padding: 16px 20px !important; min-height: 65px !important; } }
/* Mobile devices (767px and below) */ @media (max-width: 767px) { .novos-core-comparision { padding: 0 12px !important; }
.novos-core-comparision .novos-comparison-table { border-radius: 16px !important; overflow-x: auto !important; overflow-y: visible !important; -webkit-overflow-scrolling: touch !important; display: block !important; }
.novos-core-comparision h2, .novos-core-comparision .comparison-title { font-size: 30px !important; margin-bottom: 20px !important; text-align: center !important; }
/* Enable horizontal scrolling on mobile */ .novos-core-comparision .comparison-container { display: flex !important; min-width: max-content !important; width: auto !important; }
.novos-core-comparision .column { flex-shrink: 0 !important; }
.novos-core-comparision .column.first { flex: 0 0 130px !important; max-width: 130px !important; min-width: 130px !important; }
.novos-core-comparision .column:not(.first) { flex: 0 0 285px !important; min-width: 285px !important; max-width: 285px !important; }
.novos-core-comparision .heading-wrapper { padding: 14px 16px !important; min-height: 56px !important; }
.novos-core-comparision .column.first .heading-wrapper { padding: 14px 10px !important; }
.novos-core-comparision .heading-wrapper .heading, .novos-core-comparision .heading-wrapper h3, .novos-core-comparision .heading-wrapper .text { font-size: 12px !important; }
.novos-core-comparision .row { padding: 14px 16px !important; font-size: 13px !important; min-height: 56px !important; }
.novos-core-comparision .column.first .row { padding: 14px 10px !important; font-size: 11px !important; }
.novos-core-comparision .wp-block-buttons { padding: 14px 16px !important; min-height: 56px !important; } }
/* Small mobile devices (480px and below) */ @media (max-width: 480px) { .novos-core-comparision h2, .novos-core-comparision .comparison-title { font-size: 30px !important; margin-bottom: 20px !important; text-align: center !important; }
.novos-core-comparision .comparison-container { display: flex !important; min-width: max-content !important; }
.novos-core-comparision .column { flex-shrink: 0 !important; }
.novos-core-comparision .column.first { flex: 0 0 120px !important; max-width: 120px !important; min-width: 120px !important; }
.novos-core-comparision .column:not(.first) { flex: 0 0 265px !important; min-width: 265px !important; max-width: 265px !important; }
.novos-core-comparision .heading-wrapper { padding: 12px 14px !important; min-height: 52px !important; }
.novos-core-comparision .column.first .heading-wrapper { padding: 12px 8px !important; }
.novos-core-comparision .heading-wrapper .heading, .novos-core-comparision .heading-wrapper h3, .novos-core-comparision .heading-wrapper .text { font-size: 11px !important; }
.novos-core-comparision .row { padding: 12px 14px !important; font-size: 12px !important; min-height: 52px !important; }
.novos-core-comparision .column.first .row { padding: 12px 8px !important; font-size: 10px !important; }
.novos-core-comparision .wp-block-buttons { padding: 12px 14px !important; min-height: 52px !important; } }
/* Print styles */ @media print { .novos-core-comparision .novos-comparison-table { box-shadow: none !important; border: 2px solid #D0D0D0 !important; } }
NOVOS Core Clinical
Typical Longevity Supplements
.longevity-hero-section { display: flex !important; justify-content: space-between !important; align-items: center; gap: 60px !important; }
.longevity-hero-heading-wrapper { flex: 1 !important; }
.longevity-hero-title { font-family: 'Source Serif Pro', Georgia, serif !important; font-weight: 400 !important; font-style: normal !important; font-size: clamp(36px, 6vw, 48px) !important; line-height: 1.2 !important; margin: 0 !important; padding: 0 !important; text-transform: none !important; letter-spacing: -0.02em !important; }
.longevity-hero-text-orange { font-family: 'Source Serif Pro', Georgia, serif !important; color: #f25a1c !important; display: block !important; -webkit-text-fill-color: #f25a1c !important; background: none !important; margin-bottom: 0.1em !important; }
.longevity-hero-text-black { font-family: 'Source Serif Pro', Georgia, serif !important; color: #222222 !important; display: block !important; -webkit-text-fill-color: #222222 !important; background: none !important; }
.longevity-hero-tagline { font-family: 'Inter Tight', -apple-system, BlinkMacSystemFont, 'Segoe UI', sans-serif !important; font-weight: 400 !important; font-style: normal !important; font-size: clamp(14px, 2vw, 16px) !important; line-height: 1.6 !important; color: #666666 !important; text-transform: none !important; letter-spacing: normal !important; max-width: 280px !important; margin: 0 0 0 auto !important; padding: 0 !important; text-align: right !important; background: none !important; -webkit-text-fill-color: #666666 !important; flex-shrink: 0 !important; }
/* Mobile stacking */ @media (max-width: 768px) { .longevity-hero-section { display: block !important; }
.longevity-hero-tagline { margin-left: 0 !important; text-align: center !important; max-width: 100% !important; } }
12 Longevity Ingredients.
1 Clinical-Strength Formula.
The Most Effective Longevity
Drink On The Market
Calcium Alpha-Ketoglutarate (Ca-AKG)
Calcium Alpha-Ketoglutarate (Ca-AKG)
A naturally occurring metabolic intermediate involved in mitochondrial energy production. Studied for cellular protection, metabolic health, and epigenetic support, with lifespan and healthspan benefits demonstrated in animals*
Fisetin
Fisetin
A plant polyphenol studied in aging research for its role in supporting cellular senescence balance and healthy inflammatory signaling. In animal models, fisetin has been associated with lifespan extension*
Glycine
Glycine
An amino acid naturally present in collagen and metabolism. Higher glycine levels are associated with cardiovascular health, balanced inflammatory signaling, and healthy glucose metabolism. Lifespan benefits have been observed in multiple species*
Pterostilbene
Pterostilbene
A compound found in blueberries with higher bioavailability than resveratrol. Supports healthy inflammatory balance, DNA stability, and epigenetic regulation. Related compounds have demonstrated lifespan effects in animal models*
Rhodiola Rosea
Rhodiola Rosea
An adaptogenic botanical containing salidroside and other bioactives studied for cellular stress resilience. Research suggests support for mitochondrial function, AMPK and sirtuin pathways, and healthy cellular aging processes*
Micro-dosed Lithium
Micro-dosed Lithium
Trace amounts of lithium naturally occur in food and water. Epidemiological and human studies associate low-dose lithium exposure with healthy brain aging and longevity trends. Lifespan effects have also been observed in multiple species*
Magnesium Malate
Magnesium Malate
Magnesium supports hundreds of enzymatic reactions involved in energy production and metabolic health, while malate participates in the Krebs cycle. Together they support cellular energy and resilience*
Glucosamine Sulfate
Glucosamine Sulfate
Commonly known for joint health, glucosamine is also studied for its role in healthy inflammatory balance and metabolic pathways that resemble calorie-restriction biology. Lifespan associations have been observed in animals and population studies*
Hyaluronic Acid
Hyaluronic Acid
A naturally occurring structural molecule that supports skin hydration and elasticity. Oral supplementation has been shown to improve skin appearance and texture over time*
L-Theanine
L-Theanine
A green tea amino acid that promotes calm focus and healthy stress response. Studied for supporting antioxidant defenses and longevity-related cellular pathways in preclinical research*
Vitamin C
Vitamin C
An essential antioxidant that supports collagen formation, cellular protection, and epigenetic enzyme activity. Works synergistically with other nutrients to maintain cellular integrity*
Ginger Extract (Gingerols)
Ginger Extract (Gingerols)
Bioactive compounds from ginger that support healthy inflammatory balance, metabolic function, and cellular antioxidant defenses*
Calcium Alpha-Ketoglutarate (Ca-AKG)
A naturally occurring metabolic intermediate involved in mitochondrial energy production. Studied for cellular protection, metabolic health, and epigenetic support, with lifespan and healthspan benefits demonstrated in animals*
Fisetin
A plant polyphenol studied in aging research for its role in supporting cellular senescence balance and healthy inflammatory signaling. In animal models, fisetin has been associated with lifespan extension*
Glycine
An amino acid naturally present in collagen and metabolism. Higher glycine levels are associated with cardiovascular health, balanced inflammatory signaling, and healthy glucose metabolism. Lifespan benefits have been observed in multiple species*
Pterostilbene
A compound found in blueberries with higher bioavailability than resveratrol. Supports healthy inflammatory balance, DNA stability, and epigenetic regulation. Related compounds have demonstrated lifespan effects in animal models*
Rhodiola Rosea
An adaptogenic botanical containing salidroside and other bioactives studied for cellular stress resilience. Research suggests support for mitochondrial function, AMPK and sirtuin pathways, and healthy cellular aging processes*
Micro-dosed Lithium
Trace amounts of lithium naturally occur in food and water. Epidemiological and human studies associate low-dose lithium exposure with healthy brain aging and longevity trends. Lifespan effects have also been observed in multiple species*
Magnesium Malate
Magnesium supports hundreds of enzymatic reactions involved in energy production and metabolic health, while malate participates in the Krebs cycle. Together they support cellular energy and resilience*
Glucosamine Sulfate
Commonly known for joint health, glucosamine is also studied for its role in healthy inflammatory balance and metabolic pathways that resemble calorie-restriction biology. Lifespan associations have been observed in animals and population studies*
Hyaluronic Acid
A naturally occurring structural molecule that supports skin hydration and elasticity. Oral supplementation has been shown to improve skin appearance and texture over time*
L-Theanine
A green tea amino acid that promotes calm focus and healthy stress response. Studied for supporting antioxidant defenses and longevity-related cellular pathways in preclinical research*
Vitamin C
An essential antioxidant that supports collagen formation, cellular protection, and epigenetic enzyme activity. Works synergistically with other nutrients to maintain cellular integrity*
Ginger Extract (Gingerols)
Bioactive compounds from ginger that support healthy inflammatory balance, metabolic function, and cellular antioxidant defenses*
Start now
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/* Remove card styling from inner-slide */ .novos-blogs-1 .inner-slide { border: none !important; border-radius: 0 !important; background: none !important; background-color: transparent !important; }
/* Image container */ .novos-blogs-1 .splide__slide a, .novos-blogs-1 .glide__slide a { display: block; margin-bottom: 24px; }
.novos-blogs-1 .splide__slide img, .novos-blogs-1 .glide__slide img { width: 100%; height: auto; border-radius: 20px; display: block; }
/* Title text styling */ .novos-blogs-1 span[style*="font-size: 48px"], .novos-blogs-1 span[style*="48px"] { display: inline !important; font-size: 32px !important; line-height: 1.3 !important; font-weight: 400 !important; color: #4A4A4A !important; font-family: 'Inter Tight', sans-serif !important; }
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/* Responsive adjustments */ @media (max-width: 1199px) { .novos-blogs-1 span[style*="font-size: 48px"], .novos-blogs-1 span[style*="48px"] { font-size: 28px !important; }
.novos-blogs-1 span[style*="font-size: 24px"], .novos-blogs-1 span[style*="24px"] { font-size: 16px !important; } }
@media (max-width: 991px) { .novos-blogs-1 span[style*="font-size: 48px"], .novos-blogs-1 span[style*="48px"] { font-size: 26px !important; }
.novos-blogs-1 span[style*="font-size: 24px"], .novos-blogs-1 span[style*="24px"] { font-size: 15px !important; }
.novos-blogs-1 .splide__slide a, .novos-blogs-1 .glide__slide a { margin-bottom: 20px; } }
@media (max-width: 767px) { .novos-blogs-1 span[style*="font-size: 48px"], .novos-blogs-1 span[style*="48px"] { font-size: 24px !important; }
.novos-blogs-1 span[style*="font-size: 24px"], .novos-blogs-1 span[style*="24px"] { font-size: 14px !important; }
.novos-blogs-1 .splide__slide a, .novos-blogs-1 .glide__slide a { margin-bottom: 16px; } }
// Initialize the novos_slider_settings object if it doesn't exist if (typeof window.novos_slider_settings === 'undefined') { window.novos_slider_settings = {}; } window.novos_slider_settings['block_c044df319859abe307082b8811cea05e'] = {"autoplay":false,"arrows":true,"pagination":true,"perPage":3,"speed":5000,"interval":5000,"pauseOnHover":false,"type":"slide","mediaQuery":"max","smooth_scroll":true,"peek_slide":true,"add_gap":false,"gap":0,"direction":"ltr","height":0,"padding_css":"","drag":"free","autoScroll":{"speed":1,"rewind":true},"autoWidth":false,"labelAsDots":true,"breakpoints":{"1024":{"autoplay":false,"arrows":true,"pagination":false,"perPage":2,"speed":400,"interval":5000,"pauseOnHover":false,"type":"slide","mediaQuery":"max","peek_slide":true,"add_gap":false,"gap":0,"direction":"ltr","height":0,"padding_css":"","autoWidth":false,"labelAsDots":false},"768":{"autoplay":false,"arrows":true,"pagination":false,"perPage":1,"speed":400,"interval":5000,"pauseOnHover":false,"type":"slide","mediaQuery":"max","peek_slide":true,"add_gap":false,"gap":0,"direction":"ltr","height":0,"padding_css":"","autoWidth":false,"labelAsDots":false}}};
Developed by Scientists.
Formulated by a team of 7 scientists and physicians specializing in aging biology, with backgrounds at Harvard Medical School, MIT, and leading research institutions.
Trusted by Doctors.
Recommended by more than 1,500 MDs and clinicians, including physicians affiliated with Mayo Clinic.
Respected by the Press.
Featured by The Wall Street Journal as a longevity brand helping define the future of the field.
Recognized by Awards.
Recipient of multiple consumer and industry awards for innovation in science-based longevity.
Loved by our Community.
More than 10 million doses enjoyed worldwide by our growing global community.
Built and studied by world-class scientists and MD researchers dedicated to advancing the science of longevity and human healthspan.
Dr. George Church, PhD
Dr. Satomi Miwa
Dr. Pamela Maher, PhD
Dr. J. Pedro Magalhães, PhD
Dr. Robert Lufkin, MD
Start now
.people-in-grid { display: block; position: relative; padding: 0; overflow: visible;
.splide { padding: 0 !important; position: relative; width: 100%; }
.splide__track { width: 100%; position: relative; }
.splide__list { display: flex !important; align-items: stretch; gap: 0; margin: 0 !important; padding: 0 !important; list-style: none !important; transition: transform 0.8s cubic-bezier(0.45, 0, 0.25, 1) !important; }
.splide__slide { display: flex !important; flex-direction: column; width: 100%; flex-shrink: 0; padding: 0 8px; box-sizing: border-box; position: relative; transition: opacity 0.8s ease, transform 0.8s ease !important; }
.people-in-grid-member { background: #1F1B1805; display: flex; flex-direction: column; border-radius: 30px; box-shadow: 0 0 8px rgba(0, 0, 0, 0.02); overflow: hidden; height: 100%; width: 100%; transition: transform 0.3s ease, box-shadow 0.3s ease;
.image-wrapper { background: #F1F3F7; position: relative; height: 280px; width: 100%; overflow: hidden; flex-shrink: 0;
img { position: absolute; inset: 0; width: 100%; height: 100%; object-fit: contain; object-position: bottom; transition: transform 0.3s ease; } }
.content-wrapper { flex: 1; display: flex; flex-direction: column; }
.title-wrapper { margin: 0; padding: 24px 24px 16px; font-size: 20px; font-style: normal; font-weight: 600; line-height: 25px; letter-spacing: -1px; background: linear-gradient(91deg, #2F1706 -3.65%, #C18972 94.11%); background-clip: text; -webkit-background-clip: text; -webkit-text-fill-color: transparent; }
.description-wrapper { padding: 0 24px 20px; color: #7E6860; font-size: 14px; font-style: normal; font-weight: 400; line-height: 20px; letter-spacing: -0.56px; flex: 1; }
.sub-title-wrapper { padding: 0 24px 24px; display: flex; flex-direction: row; gap: 8px; align-items: center;
.icon { display: flex;
img { height: 25px; width: 25px; } }
.sub-title-text { color: #B6ADA9; font-size: 16px; font-style: normal; font-weight: 600; line-height: 18px; letter-spacing: -0.64px; } }
&.hide-mobile, &.hide-tablet, &.hide-desktop { display: flex !important; } }
.splide__slide.is-active .people-in-grid-member:hover { transform: translateY(-4px); box-shadow: 0 8px 16px rgba(0, 0, 0, 0.1); }
.splide__nav-wrapper { display: flex !important; align-items: center; justify-content: center; gap: 40px; padding: 32px 0 0; width: 100%; margin: 0 auto; visibility: visible !important; opacity: 1 !important;
.splide__arrow { background: none !important; border: none !important; width: auto !important; height: auto !important; display: flex !important; align-items: center !important; justify-content: center !important; position: static !important; top: auto !important; left: auto !important; right: auto !important; bottom: auto !important; transform: none !important; cursor: pointer !important; padding: 8px !important; margin: 0 !important; box-shadow: none !important; transition: color 0.3s ease, transform 0.3s ease !important; flex-shrink: 0 !important; opacity: 1 !important; pointer-events: auto !important; font-size: 40px !important; color: #2F1706 !important; font-weight: bold !important; line-height: 1 !important;
&:hover:not(:disabled) { color: #C18972 !important; transform: scale(1.15) !important; }
&:disabled { opacity: 0.2 !important; cursor: not-allowed !important; } } }
.splide__pagination { display: none !important; } }
@media (max-width: 767px) { .people-in-grid { .people-in-grid-member { .image-wrapper { height: 220px; } }
.splide__slide { padding: 0 6px; }
.splide__nav-wrapper { gap: 32px; padding: 24px 0 0;
.splide__arrow { padding: 6px !important; font-size: 32px !important; } } } }
@media (min-width: 768px) and (max-width: 1199px) { .people-in-grid { .people-in-grid-member { .image-wrapper { height: 240px; } }
.splide__slide { padding: 0 8px; }
.splide__nav-wrapper { gap: 36px; padding: 28px 0 0;
.splide__arrow { padding: 7px !important; font-size: 36px !important; } } } }
@media (min-width: 1200px) { .people-in-grid { .people-in-grid-member { .image-wrapper { height: 280px; }
.title-wrapper { padding: 32px 32px 20px; font-size: 22px; line-height: 28px; }
.description-wrapper { padding: 0 32px 24px; font-size: 14px; line-height: 22px; }
.sub-title-wrapper { padding: 0 32px 32px; } }
.splide__slide { padding: 0 8px; }
.splide__nav-wrapper { gap: 40px; padding: 32px 0 0;
.splide__arrow { padding: 8px !important; font-size: 40px !important; } } } }
@media (min-width: 1440px) { .people-in-grid { .people-in-grid-member { .image-wrapper { height: 300px; } }
.splide__nav-wrapper { gap: 48px; padding: 36px 0 0;
.splide__arrow { padding: 10px !important; font-size: 44px !important; } } } } }
(function () { var INTERVAL = 4000;
function isTarget(el) { return !!(el && el.closest && (el.closest('.novos-sceintist-clinical') || el.closest('.novos-scientist-clinical'))); }
function addPauseHandlers(el, instance) { var holding = false;
el.addEventListener('mousedown', function () { holding = true; try { instance.Components.Autoplay.pause(); } catch (e) {} });
el.addEventListener('touchstart', function () { holding = true; try { instance.Components.Autoplay.pause(); } catch (e) {} }, { passive: true });
document.addEventListener('mouseup', function () { if (!holding) return; holding = false; try { instance.Components.Autoplay.play(); } catch (e) {} });
document.addEventListener('touchend', function () { if (!holding) return; holding = false; try { instance.Components.Autoplay.play(); } catch (e) {} }); }
// Patch Splide.prototype.mount so our interval is set BEFORE autoplay starts function patchSplide() { if (!window.Splide || Splide.prototype._novosPatched) return; Splide.prototype._novosPatched = true;
var orig = Splide.prototype.mount; Splide.prototype.mount = function (Components, Extensions) { if (isTarget(this.root)) { // Set interval before components initialize — autoplay picks this up on mount this.options.interval = INTERVAL; this.options.pauseOnHover = true; this.options.pauseOnFocus = true; } var result = orig.call(this, Components, Extensions); if (isTarget(this.root)) { addPauseHandlers(this.root, this); } return result; }; }
patchSplide();
// Also patch on DOMContentLoaded in case Splide loads late document.addEventListener('DOMContentLoaded', patchSplide); })();
/** * Novos Scientist Clinical - Splide Slider Initialization * Desktop: 3 cards, Tablet: 2 cards, Mobile: 1 card * With peek effect, smooth sliding animations, and auto-play */
(function() { 'use strict';
function ensureBottomArrows(splide, splideWrapper) { if (!splide || !splideWrapper) { return; }
var navWrapper = splideWrapper.querySelector('.splide__nav-wrapper'); if (!navWrapper) { navWrapper = document.createElement('div'); navWrapper.className = 'splide__nav-wrapper'; navWrapper.style.display = 'flex'; navWrapper.style.alignItems = 'center'; navWrapper.style.justifyContent = 'center'; navWrapper.style.gap = '40px'; navWrapper.style.padding = '32px 0 0'; splideWrapper.appendChild(navWrapper); }
var prevButton = navWrapper.querySelector('.splide__arrow--prev'); var nextButton = navWrapper.querySelector('.splide__arrow--next');
if (!prevButton) { prevButton = document.createElement('button'); prevButton.type = 'button'; prevButton.className = 'splide__arrow splide__arrow--prev'; prevButton.setAttribute('aria-label', 'Previous'); prevButton.innerHTML = '←'; prevButton.style.cssText = 'background:none!important;border:none!important;font-size:40px!important;color:#2F1706!important;font-weight:bold!important;cursor:pointer!important;padding:8px!important;margin:0!important;'; navWrapper.appendChild(prevButton); }
if (!nextButton) { nextButton = document.createElement('button'); nextButton.type = 'button'; nextButton.className = 'splide__arrow splide__arrow--next'; nextButton.setAttribute('aria-label', 'Next'); nextButton.innerHTML = '→'; nextButton.style.cssText = 'background:none!important;border:none!important;font-size:40px!important;color:#2F1706!important;font-weight:bold!important;cursor:pointer!important;padding:8px!important;margin:0!important;'; navWrapper.appendChild(nextButton); }
if (!prevButton.dataset.boundClick) { prevButton.addEventListener('click', function(e) { e.preventDefault(); splide.go(''); }); nextButton.dataset.boundClick = '1'; }
function updateDisabled() { var perPage = (splide.options && splide.options.perPage) ? splide.options.perPage : 1; var endIndex = splide.length - perPage; if (endIndex perPage; navWrapper.style.display = shouldShow ? 'flex' : 'none';
var isPrevDisabled = splide.index = endIndex;
prevButton.disabled = isPrevDisabled; nextButton.disabled = isNextDisabled; prevButton.style.opacity = isPrevDisabled ? '0.2' : '1'; nextButton.style.opacity = isNextDisabled ? '0.2' : '1'; }
updateDisabled();
if (!splideWrapper.dataset.boundNavEvents) { splide.on('mounted', updateDisabled); splide.on('moved', updateDisabled); splide.on('updated', updateDisabled); splide.on('resized', updateDisabled); splideWrapper.dataset.boundNavEvents = '1'; } }
function initNovosSlider() { if (typeof Splide === 'undefined') { setTimeout(initNovosSlider, 100); return; }
var wrappers = document.querySelectorAll('.novos-sceintist-clinical, .novos-scientist-clinical');
if (!wrappers.length) { return; }
var grids = []; wrappers.forEach(function(wrapper) { var grid = wrapper.querySelector('.people-in-grid'); if (grid) { grids.push(grid); } });
if (!grids.length) { return; }
grids.forEach(function(grid, index) { if (grid.classList.contains('splide-initialized')) { return; }
var members = grid.querySelectorAll('.people-in-grid-member');
if (!members.length) { return; }
var splideWrapper = document.createElement('div'); splideWrapper.className = 'splide'; splideWrapper.id = 'novos-scientist-slider-' + index;
var splideTrack = document.createElement('div'); splideTrack.className = 'splide__track';
var splideList = document.createElement('ul'); splideList.className = 'splide__list';
members.forEach(function(member) { var slide = document.createElement('li'); slide.className = 'splide__slide'; slide.appendChild(member.cloneNode(true)); splideList.appendChild(slide); });
splideTrack.appendChild(splideList); splideWrapper.appendChild(splideTrack);
grid.innerHTML = ''; grid.appendChild(splideWrapper);
try { var isMobile = window.innerWidth <= 767; var splide = new Splide('#' + splideWrapper.id, { type: 'loop', perPage: 3, perMove: 1, gap: '16px', padding: { right: '10%' }, pagination: false, arrows: false, drag: true, speed: 800, easing: 'cubic-bezier(0.25, 0.1, 0.25, 1)', focus: 0, trimSpace: false, autoplay: true, interval: 3000, pauseOnHover: true, pauseOnFocus: true, breakpoints: { 1199: { perPage: 3, gap: '16px', padding: { right: '8%' }, autoplay: true, interval: 3500 }, 991: { perPage: 2, gap: '12px', padding: { right: '12%' }, autoplay: true, interval: 3000 }, 767: { perPage: 1, gap: '8px', padding: { left: '5%', right: '15%' }, autoplay: true, interval: 2500, pauseOnHover: false } } }); splide.mount(); setTimeout(function() { ensureBottomArrows(splide, splideWrapper); }, 100); splide.on('mounted', function() { ensureBottomArrows(splide, splideWrapper); }); splide.on('updated', function() { ensureBottomArrows(splide, splideWrapper); }); splide.on('resized', function() { ensureBottomArrows(splide, splideWrapper); }); grid.classList.add('splide-initialized'); } catch (error) { // Silent error handling } }); } if (document.readyState === 'loading') { document.addEventListener('DOMContentLoaded', function() { setTimeout(initNovosSlider, 500); }); } else { setTimeout(initNovosSlider, 500); } })();
Invest in your health with NOVOS Core Clinical
a clinically studied longevity formulation among the most rigorously studied in humans, globally.
When it comes to your future health, proof matters.
Core Clinical is science you can trust and results you can feel.
Start now
Questions, answered.
NOVOS Core Clinical contains 12 research-backed longevity ingredients:
- Vitamin C
- Magnesium Malate
- Calcium Alpha-Ketoglutarate
- Glycine
- Glucosamine Sulfate
- Rhodiola
- L-Theanine
- Hyaluronic Acid
- Fisetin
- Gingerol
- Pterostilbene
- Micro-dosed Lithium
The Orange flavor also includes erythritol, malic acid, stevia, and natural flavors. Core is vegan, non-GMO, sugar-free, and free from artificial colors and preservatives.
NOVOS Core Clinical is designed for adults of all ages who want to proactively support healthy aging.
- Younger users benefit from early support, while older adults may notice more immediate short-term effects.
NOVOS Core Clinical is free from:
- Dairy, gluten, soy, nuts, and shellfish
- Sugar, calories, and GMOs
- Preservatives and 14 EFSA-listed allergens
It suits vegan, vegetarian, Mediterranean, keto, gluten-free, and NOVOS Longevity Diet guidelines.
A small percentage of users experience temporary stomach discomfort when starting Core. Taking it with food, splitting the dose, or mixing it with extra water typically resolves this within a few weeks.
NOVOS recommends avoiding Core during pregnancy and breastfeeding as a precaution.
No. Store Core Clinical at room temperature in a cool, dry place.
Longevity Hackers: A Documentary on How to Stop Aging
NOVOS CEO Chris Mirabile joins Tony Robbins, Mark Cuban, and leading longevity scientists in Longevity Hackers, a groundbreaking documentary that uncovers the science and biohacking secrets adding not just years but healthy, fulfilled years to life.
*These statements have not been evaluated by the Food and Drug Administration. This product/information is not intended to diagnose, treat, cure, or prevent any disease. *All statements reflect support for normal, healthy biological function and are not intended to diagnose, treat, cure, or prevent disease.
Details
- Brand
- novos_labs
- Category
- Daily health
- Reference
- novos-core-clinical-lp
